Public Health 19 , 13280 (2022)
In dermatology, CPPs exhibit therapeutic potential by regulating collagen synthesis, modulating melanogenesis, and alleviating inflammation in atopic dermatitis
In fact, NO at high levels inhibits heme insertion in hemoglobin, NO synthases, and heme thiolate enzymes, such as cytochrome P450s (CYP) in different manners (i.e., through the direct binding to the heme iron or to covalent modifications in heme transfer proteins) [147,148,149]
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